Pantnagar Journal of Research

Abstract

Crimean Congo Haemorrhagic Fever (CCHF) is a potentially fatal tick born viral zoonotic disease affecting humans in a wide geographical area. In India, it is considered as an emerging viral zoonosis and repeated outbreaks are noticed especially in the Gujarat state since 2011. The current study is focussed on the phylogenetic relationship based on the genomic sequence of nucleocapsid segment of various strains of CCHF virus (CCHFV) circulated in India over past 10 years. It was found that there were considerable differences in the nucleotide sequences and the Indian strains are found to be related to two different phylogenetic groups i.e., Asia-1 and Asia-2. It suggests the transboundary nature of the disease which may be well coordinated with the travel history of the patients affected.